Identification of a genetic risk factor for idiopathic dilated cardiomyopathy. Involvement of a polymorphism in the endothelin receptor type A gene
نویسندگان
چکیده
*Centre de Recherche de l’Association Claude Bernard and Université Paris VI (UPRES EA no 2390), †Service de Cardiologie, ***Service de Chirurgie Cardiaque, ‡‡‡INSERM U153, Hôpital Pitié-Salpêtrière, Paris; ‡INSERM SC7 and §INSERM U258, Hôpital Broussais, Paris; QMONICA project-France, †††INSERM U249, Montpellier; Services de Cardiologie and/or Chirurgie Cardiaque, ¶Hôpital Ambroise Paré, Boulogne; **Hôpital Laennec, Nantes; ††Hôpital Cardiologique, Lille; ‡‡Hôpitaux de Brabois, Nancy; §§Hôpital Haute-Pierre, Strasbourg; QQHôpital Louis Pradel, Lyon; ¶¶Hôpital Henri Mondor, Creteil; §§§Hôpital Boucicaut, Paris, France
منابع مشابه
A polymorphism in the endothelin-A receptor gene predicts survival in patients with idiopathic dilated cardiomyopathy.
AIMS The endothelin system plays a role in the complex pathophysiology of idiopathic dilated cardiomyopathy. We investigated whether genetic polymorphisms of the endothelin system might be associated with dilated cardiomyopathy-related cardiac phenotypes and differences in disease outcome. METHODS One hundred and twenty-five unrelated dilated cardiomyopathy patients of a well characterized di...
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